![]() With tool free headrail installation, these easy install Roman Blinds simply click into place with no drills needed. Our revolutionary no drill Roman Blinds make updating any recess window effortless. Shop Click2Go Pleated Blinds Click2Go Roman Blinds ![]() Thermally efficient with drill free headrail installation, the clever pleated design works hard to help keep your space cool in summer and warm in winter, plus the light filtering and blackout options make light control a breeze. Take care not to damage the slot of the curtain track when drilling or mounting the track.Our easy to install no drill Click2Go Pleated Blinds are the perfect choice for recess windows. After confirming that the pilot hole is centered in the correct position, use an appropriate bit that creates holes that will accommodate your screws of bolts. Standard drill bits work fine on all aluminum tracks. Using a small bit, drill pilot holes centered in the slot through the top of the track. To drill holes, identify where the holes should be positioned and mark the track. Most curtain tracks do not have the mounting holes pre-drilled. For systems where a master carrier is not offered, you can also add an additional carrier between the 1st and 2nd carrier on each panel, allowing a free carrier that can be used to support a baton or wand. Some curtain track systems offer master carriers that allow for easy attachment of a wand or baton to draw curtains or draperies open or closed. All Curtain-Track systems are hand-drawn systems. CORD DRAWN TRAVERSE RODS AND TRACKSĬ does not offer cord drawn systems. When installing tracks to be used with two-way draw curtains that meet in the middle, it is advisable to center the seam so that carriers are not traveling over the seam. Often, the use of a laser level can assist in marking consistent mounting locations to assist with this alignment. In either case, it is important to fully align the tracks to minimize the seam and thus reduce the likelihood that carriers jam in transit. Some track systems offer splicers that connect the track sections, while others require that the tracks be aligned and abutted during installation without additional hardware. ![]() Wider applications may require that tracks be mounted end to end. Anchors can also be used when sheetrock offers the only attaching surface. It is advisable to attach tracks and brackets to ceiling joists and wall studs or other solid supporting surfaces whenever possible. When selecting screws/bolts that are to be inserted through the slot in a track, be sure to consider that the head of the screw/bolt must fit clearly through the slot without marring the track. FASTENERSĬ does not sell mounting fasteners (screws, toggle bolts, anchors, etc.) as specific installations vary widely, and can best be addressed at your local hardware store. Review the topics below for more information, and download the specific installation instructions to aid you with your project. You should use good judgment in assessing the mounting surface to be sure the tracks will be adequately supported. With the use of simple tools (drill, screwdriver, laser level, miter saw), the installations can be completed fairly quickly. ![]() The installation of these curtain track systems is not complicated and can be completed by most Do-It-Yourselfers (DIY’s). ![]()
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![]() ![]() The camera’s three microphones can extend as much as 8 to 14 feet out from the camera, able to pick up the voices of those furthest away from the picture.You can add text in real time and change font, color and position. Thanks to its intuitive design, the 960-001201 is also able to act as a speakerphone, and with its ability to connect with Bluetooth-enabled devices, this is a perfect feature.Select Camera. Select the checkbox next to an app to allow it to access your camera. Deselect the checkbox to turn off access for that app. ![]() If you turn off access for an app, you’re asked to turn it on again the next time that app tries to use your camera.Are you a big fan of video streaming on YouTube, Twitch and Facebook? Or perhaps you are shifting to online remote work during this special period, and are in searching for webcam applications that can capture yourself and desktop screens simultaneously.The best conference room cameras should be practical, easy to operate and deliver a sharp viewing experience. That’s even more important if you are sharing a video conference with a global audience, connecting from multiple locations simultaneously which is a popular feature with the more sophisticated conference webcams.Robust webcam software should allow you to capture high quality content, apply effects and filters in case you have bad lightning or a tired face. Put background processes to sleep so they don’t steal your PC’s resources from the If you want to format a hard drive or USB flash drive on your computer, disk formatting tool is the best choice. In this article, we will introduce 5 disk formatting tools for Windows and Mac to help you securely format hard drive/USB flash drive or memory card on a PC or a Mac. Top 5 Disk Formatting Tool for Windows/MacThe best way to clear the C drive is by cleaning its temporary data at regular intervals by using the Disk Cleanup Utility. ![]() There are multiple ways to access the Disk Cleanup app. One of the easiest ways is to look for it from the start menu. So, here are our top picks of the best Mac cleaner software in 2021.Once the Disk Cleanup application is launched, you need to select the drive you wish to clean.Clean up your PC and speed up Windows (10, 8, 7, and Vista) in 3 easy steps with the top rated PC cleaner. You'll find tons of applications out there offering disk cleanup for Mac. Mount the volume (if it is not already mounted).MacOS Mojave 10.14 has arrived: How to download, best new, mojave macos apple.You can easily detect when a device is performing subpar and, and with the spinning disk, you can see is transfer speeds deteriorates over time.Ĭhoosing the best one that matches your needs can get difficult. Mac Os X Mojave Download everscore, mojave mac os dmg macos Atari VCS.In Blackmagic select the disk image mounted. Since the “volume” is on your Startup Disk, you will see how fast it drive is. On my 2016 MacBook Pro, I am seeing speeds like 1,000+ MB/s write, and 1100+ MB/S read. Blackmagic Disk Speed Test Dmg Mac Os Dmg MacosI have tried this on my older mackbooks with SSD and they do scale down as the device is older. Designed for Macintosh, this tool uses a standard method to determine the reading and writing speed of your hard drive. In order to do this, it only fills in the free space on your hard disk by a sample of data and begins the assessment to determine these two.When Blackmagic tries to read the Startup Disk, you get the message that the device is not writeable, hence you cannot rate the the transfer rates of the drive.Download Blackmagic Disk Speed Test for macOS 10.10.0 or later and enjoy it on your Mac. ![]() Disk Speed Test is an easy to use tool to quickly measure and certify your disk performance.Blackmagic Disk Speed Test Free Disk Speed Test is an easy to use tool to quickly measure and certify your disk performance for working with high quality video. Blackmagic Disk Speed Test is special software that allows MAC users to measure their disk perfor.Blackmagic Disk Speed Test for MAC OS. Black magic speed 2.2 dmg social advice Mac users interested in Black magic speed 2.2 dmg generally download: Blackmagic Disk Speed Test 3.1 Free. Blackmagic Disk Speed Test 3.1 - Measure disk performance for video work.Blackmagic Disk Speed Test is not available for Windows but there are plenty of alternatives that runs on Windows with similar functionality. ![]() ![]() ![]() For instance, you can rebuild MBR, convert MBR to GPT, etc. Then boot from the burned bootable drive.Īfter launching MiniTool Partition Wizard, you can fix errors with your hard drive. At first, you need to create a bootable CD/DVD/USB Drive with its Bootable Media Builder feature. If your computer becomes unbootable because of hard disk errors, MiniTool Partition Wizard helps. You can download one from them according to your demand for your PC and then make ISO files. Here, several best free ISO creators are introduced. As implied by its name, ISO maker is built to make ISO files. Like Windows 10 Media Creation Tool and Chromebook Recovery Utility, ISO creators can make files that can be used to boot a unbootable computer. You can make ISO files with ease with the help of ISO makers. Hence, the number of users who create ISO files from CDs, DVDs, BDs, or selected files and folders increases quickly. In a word, ISO files is an ideal way to store and distribute discs. Besides, ISO files are often used to distribute extremely large programs over the Internet. With ISO files, you can share multiple files as one with others online. As you know, CDs and DVDs are being used less and less. ISO files refer to files that contain similar data as an optical disk but are stored on the hard drive. You can pick one ISO creator from given options. If you are looking for an ISO maker, this post of MiniTool is worth reading. This post will introduce ISO files briefly and then show you 6 best free ISO creators. ![]() ![]() ![]() Just like you can take advantage of lazy or distracted lawyers by forcing answers to your interrogatories, you can also gain an advantage by not answering interrogatories that are arguably objectionable. ![]() Under Maryland law, this onus is on the party receiving the objection to force the issue. Practically, discovery objections also allow you to avoid answering difficult questions. There are times when you should not give complete answers to an interrogatory because the question is objectionable. If we do not hold defendants' feet to the fire, we toss away a powerful tool to box in defendants for trial - and provide evidence that we are not giving the case the care and attention it deserves.īut this is an adversarial process. This page provides a cheat sheet for discovery objections for lawyers.Įlsewhere on this website, we talk about the importance of forcing defendants to provide meaningful answers to interrogatories, requests for the production of documents, and other discovery responses and requests. 11 26 Sanitation & Recycling Indus., Inc. County of San Luis Obispo, 548 F.3d 1184 (9th Cir. City & County of San Francisco, 196 F.R.D. 18Ĭertain of the Specific Questions and Answers Designated by the Plaintiff Are Also Inadmissible for Various Reasons. 17 Testimony Regarding the Experiences of Foreign Militaries Is Irrelevant. 16 Testimony Regarding Enlistment Waivers for Convicted Felons Is Irrelevant. Testimony Regarding Research and Developments that Occurred After Enactment of 10 U.S.C. 13 At Least Three Specific Areas Inquired into in the 30(b)(6) Depositions Are Irrelevant. 12 The Designated Testimony of the 30(b)(6) Witnesses Is Irrelevant to the Extent it Constitutes the Personal Views of the Witnesses. Presenting Testimony by Six Former Service Members Would Constitute "Needless Presentation of Cumulative Evidence". All of the Contemplated Lay Witness Testimony Regarding the Merits Is Irrelevant in this Facial Challenge. Plaintiff Failed to Disclose the Identities of Eight 8 of its Lay Witnesses as Required by the Rules. MEMORANDUM OF POINTS AND AUTHORITIES TABLE OF CONTENTSĤ INTRODUCTION. 20044 Telephone: (202) 353-0543 Facsimile: (202) 616-8202 Attorneys for Defendants United States of America and Secretary of Defense Department of Justice, Civil Division Federal Programs Branch 20 Massachusetts Ave., N.W. ![]() Respectfully submitted, TONY WEST Assistant Attorney General ANDRÉ BIROTTE, JR United States Attorney JOSEPH H. BOX 883, BEN FRANKLIN STATION WASHINGTON, D.C. 13 Dated: J14 15 16 17 18 19 20 21 22 23 24 25 26 27 28ĭEFENDANTS' NOTICE OF MOTION AND MOTION IN LMINE TO EXCLUDE LAY WITNESS TESTIMONY UNITED STATES DEPARTMENT OF JUSTICE CIVIL DIVISION, FEDERAL PROGRAMS BRANCH P.O. This Motion is made following the conference of counsel pursuant to Local 11 12 Rule 7-3, which took place by telephone on June 8, 2010. The Motion 8 will be based upon these moving papers, the attached Memorandum of Points and 9 Authorities in support of the Motion, and upon such other and further arguments, 10 documents, and grounds as may be advanced in the future. Phillips, United States District Judge, 5 Defendants United States of America and the Secretary of Defense (collectively, 6 "Defendants"), by and through counsel, will move in limine to exclude certain lay 7 witness testimony that Plaintiff intends to offer into evidence at trial. NOTICE OF MOTION AND MOTION IN LIMINE TO EXCLUDE LAY WITNESS TESTIMONY NOTICE IS HEREBY GIVEN that on June 28, 2010, at 2:30 p.m., in theĤ Courtroom of the Honorable Virginia A. UNITED STATES DEPARTMENT OF JUSTICE CIVIL DIVISION, FEDERAL PROGRAMS BRANCH P.O. Notice of Motion and Motion in Limine to Exclude Lay Witness Testimony 2. GATES, Secretary of 18 Defense, 19 20 21 22 23 24 25 26 27 28ĭEFENDANTS' NOTICE OF MOTION AND MOTION IN LMINE TO EXCLUDE LAY WITNESS TESTIMONYįiled herewith: 1. BEFORE: Judge Phillipsġ7 UNITED STATES OF AMERICA AND ROBERT M. CV04-8425 VAP (Ex) DEFENDANTS' NOTICE OF MOTION AND MOTION IN LIMINE TO EXCLUDE LAY WITNESS TESTIMONY DATE: JTIME: 2:30 p.m. UNITED STATES DISTRICT COURT FOR THE CENTRAL DISTRICT OF CALIFORNIA EASTERN DIVISION Plaintiff, ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) No. 20044 Telephone: (202) 353-0543 9 Facsimile: (202) 616-8460 E-mail: 10 Attorneys for Defendants United States 11 of America and Secretary of Defense 12 13 15 16 v. Department of Justice Civil Division 7 Federal Programs Branch Post Office Box 883 8 Washington, D.C. United States of America et alġ TONY WEST Assistant Attorney General 2 ANDRÉ BIROTTE, Jr. ![]() ![]() ![]() They circumvent a couple of issues games have always had, namely appropriate punishment for failing, and a risk-reward system. I can safely say this is one of the only games where I felt a sense of accomplishment after every single boss was slain, because there were no cheap tactics to speak of, be it on the player’s part or the bosses’. Players that get frustrated easily might be turned off by some of the difficulty, but I never found any of the bosses to be unfair in their tactics. Reflexes are definitely put to the test, especially considering most bosses are unique in their move sets, meaning each of the 30 boss battles provide a whole new challenge to overcome. Along the way I’d be killing enemies to collect Geo, the in-game currency, as well as discovering previously unreachable areas and secrets, including a slew of challenging bosses.īosses aren’t pushovers, even with grinding to get some of the better equipment to help out. Backtracking to areas I’d been never felt tedious. This meant that by the time I’d reached the credits for the first time, which took me 27 well-spent hours, I was pretty comfortable navigating most of the kingdom without looking at my map. Most areas of the map are accessible early on, with certain areas in them only being accessible after acquiring items and abilities elsewhere. Speaking of not being spoon fed, Hollow Knight encourages you to go explore as you wish. In most games buying maps is possibly one of the most boring experiences, but in Hollow Knight, I got excited every time I heard the faint hum of the cartographer from afar, growing louder as I got closer to his often hidden locations. One character you’ll constantly run into is a cartographer, who can always be located by following pieces of paper found on the ground and the song he hums. ![]() ![]() Even the general sound design is great, as every enemy has different realistic scuttling sounds, and many characters speak in seemingly made-up languages I found myself quoting by the end of the game. There are tracks here that I’d rank beside the music of Zelda and Star Wars. On top of that, the soundtrack is one of the most memorable and whimsical scores I’ve heard in a long time. After only seeing videos and screenshots of the game’s first area, a dreary cave where everything is a shade of blue, I had my breath taken away the moment I got to the second area, a jungle. One area has ghosts floating in the foreground, while others have sprawling jungles or caves with layers that move independently of each other to create much livelier levels than most 2D games can offer. All of the 100-plus characters are animated to be adorable and/or hideous, and the different areas of the humongous map each have their own art styles with some of the best use of parallax I’ve ever seen. Hollow Knight is a beautifully hand-drawn metroidvania that is equal parts fun, difficult, cute, and horrifying. ![]() ![]() The ROI on that effect may be immeasurable, but how much would another MI marketing element have added to the saturation bombing weĪnd of course, Bad Robot has another little business cooking here, so why blow it? Users can upgrade with 99-cent packs of new effects, a tool for Here –- these guys are cool, creative and now mobile-savvy. That may be good enough for Bad Robot, and adding in an easy, predictable pitch for a specific movie might break the indirect messaging already Bad Robot gets the ambient benefit of simply demonstrating its technical prowess in one of the increasingly rare “gotta see this” apps that makes theĭazzled user wonder who the hell made this app. The opportunity to slip in a little promo of Cruise repelling from that Dubai skyscraper After all, here is this platform that is proving to be as popular as most top game apps. I send laser-guided missiles into my desktop stapler regularly.Īs a branding exercise, Action Movie FX might be seen asĪ missed opportunity. Reticule to a tornado, a mass of machine guns, or a ditched helicopter. The iPhone camera and then superimpose (pretty damn seamlessly, I may add) clichéd action sequences - from incoming missiles laying waste to a ground zero that you pinpoint with a target The app allows you to take short video clips with Instagram meets Michael Bay - or, well, J.J. ![]() One of the best implementations of video editing/overlay techniques I have seen on a smartphone. The app does what Abrams and company actually do best - cool action. ![]() And thank God (or the "Eighth Dynamic," as Scientology might have it) - no Tom Cruise. ![]() Instead, the company’s Action Movie FX app has been a presence scoring high on the App Store’s Entertainment chart for about a month now. Throwaway that is clever for all of ten seconds. Ghost Protocol" has another "Star Trek" movie coming and the "Person of Interest" TV series now on air.īut the Bad Robot Interactive unit chose not to put out another cheesy movie promo app The talented action movie director and TV producer and owner of the Bad Robot Productions company that just released "Mission Impossible: ![]() ![]() This makes wearing underwear as if you’re not wearing anything at all. You already got that, but Addicted underwear is not just your average underwear: it is so much more! Addicted underwear is created, designed and made in Barcelona with the best quality fabrics available. ![]() Right? Well, if you haven’t tried the hot and sexy men’s underwear from Addicted, you haven’t worn the closest to perfection yet. MEN’S WORLD NUMBER ONE BRAND IN COMFORTABLE AND SEXY UNDERWEARĪlright, you say that you are the man who has it all, seen it all and has done it all. Addicted uses the highest quality materials and accessories in creating the best gay clothing brand available in the market, of course the Addicted brand is right out there together with its older brother Come and check out all technologies created by the Addicted team under the Shapewear category at addicted.es and you'll be amazed of the innovations that come with this world-famous gay brand. Addicted fashion clothing is comfortable, original, stylish and elegant. pack-up technology which enhances your bulge and prevents the 'shrunken-sausage-look' when coming out of the water after a refreshing dip. The guys love to wear quality swimwear with e.g. Thanks to many different technologies, created by the Addicted Research, Development and Innovation team, the boys of the world can wear this Addicted clothing brand with pride, being proud to be able to show what they've got to offer. Nowadays, more and more straight guys are willing to wear more daring swimwear, more colorful underwear and in general, clothing that shows your male proudness with pride. ![]() Gay men are proud of who and what they are! Addicted is for the boys who like to show their sexiness, who aren't shy for being looked at in admiration at the beach, pool or party by other boys. Why? Because the gays love more flamboyant clothing, more expressive sexy wear and they are more into a certain life style and willing to show what they've got. The brand Addicted, as said before, was and is a brand created for the gay market. MOST COMFORTABLE, ORIGINAL, STYLISH, ELEGANT, SEXY GAY CLOTHING AND FASHION Designer fashion wear is Addicted fashion wear. Nowadays, Addicted is the top model brand within men’s fashion, and more specifically, within the gay sector, one that comes to mind immediately when thinking about gay men’s fashion. Several times a year new underwear, swimwear and sportswear designs are outed, catering to its gay fashion clientele. For many years now, Addicted has not only been designing trendy gay swimwear, but has also been expanding its collections. Collection, which came to life back in 2006. ![]() In a short amount of time, the gay brand experienced rapid growth, aided by the success of it's slightly older gay brother: The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.Addicted was founded in 2009 in Barcelona, dedicating itself to the creation, design and manufacturing of gay men’s top quality swimwear. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. ![]() This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. ![]() ![]() are borne on far out into space (Lds Quotes) Like every beginner, I have thought you could beat, pummel and thrash an idea into existence. Who knows how many fleshly forms the heir of heaven occupies before he can be brought to understand the value of that silence and solitude of spiritual worlds? (Lds Quotes) There are infinite worlds both like and unlike this world of ours. That is the smile: that what might not be, is (Lds Quotes) All human beings go through a previous life. Such a school demands from the teacher that he be a kind of artist in his province (Lds Quotes) Chess holds its master in its own bonds, shackling the mind and brain so that the inner freedom of the very strongest must suffer (Lds Quotes) Because a star explodes and a thousand worlds like ours die, we know this world is. The stupendous order of nature, the revolution of a hundred millions of worlds around a million of stars, the activity of light, the life of all animals, all are grand and perpetual miracles (Lds Quotes) Who then can calculate the path of the molecule? how do we know that the creations of worlds are not determined by the fall of grains of sand? (Lds Quotes) The point is to develop the childlike inclination for play and the childlike desire for recognition and to guide the child over to important fields for society. I wish you, my beloved friends, a very merry Christmas and a joyful season of helping others see and feel the light of Jesus Christ.Text Quotes All is a miracle. These are gifts that remind us and them of the true reason for the season, the gift of God’s son, Jesus Christ, who was born to cast out all fear and bring everlasting light and joy to all that follow him. No gifts will mean as much as acts of pure love you offer to the lonely, the worn down and the weary. I invite you to make room in your heart for those around you who may be struggling to see the light of the Savior and to feel his love. That is why we like to share the light of Jesus Christ when so many around us are burdened with fear and uncertainty. This Christmas, some are still waiting for the lights to come on again. Given all that we have experienced during this past year and more, may I share a message about how we can help transform lives during this special time of year? As you watch, I invite you to ponder the ways you personally can reach out and help others experience the light of Jesus Christ this Christmas. The Christmas season is near and dear to my heart, as I know it is to many of you. It also includes red Giving Machines, vending machine style machines that allow people to buy a donation to local or global charities instead of candy bar or a Coke. The international initiative centered at includes a calendar with service ideas for each day leading up to Christmas. President Nelson’s video matched the theme - “ light the world with love” - of the church’s annual Light the World Christmas initiative. ![]() In that message, he prescribed gratitude and prayer as a healing remedy for spiritual and societal problems and asked people around the world to flood social media for the following week with “a wave of gratitude” using the hashtag #GiveThanks. The video was shorter but similar in some ways to President Nelson’s 2020 video message before Thanksgiving. It is HIS light and HIS love that will heal our hearts during this season-and during all of life’s challenges. This Christmas, I invite you to share the light of the Savior Jesus Christ with those around you. These are gifts that remind us and them of the true reason for the season, the gift of God’s son, Jesus Christ, who was born to cast out all fear and bring everlasting light and joy to all that follow him.” “No gifts will mean as much as acts of pure love you offer to the lonely, the worn down and the weary. “I invite you to make room in your heart for those around you who may be struggling to see the light of the Savior and to feel his love,” President Nelson said. The video included scenes depicting both happy families and people who appeared lonely and down. President Nelson said his message was an invitation for people to ponder how they can help those burdened with fear and uncertainty experience the light of Jesus Christ this Christmas season. ![]() tornado outbreak killed at least 88 people in six states. The message also came as thousands remained without power after last weekend’s deadly U.S. President Nelson builds bridge from #GiveThanks to #LightTheWorld. ![]() Watch: President Nelson calls for healing ‘wave of gratitude’ on social media for world’s ‘many ills’. ![]() ![]() ![]() We list an MSRP on our products that we sell ourselves and that sell through our wholesale partners. *MSRP is our Manufacturer's Suggested Retail Price at which we suggest our collections be initially offered. Valid on Skip Hop product in Carter’s stores only. 50% OFF second item of equal or lesser value. ![]() *25% OFF ENTIRE SITE: Savings based on MSRP. *20% OFF ENTIRE SITE: Savings based on MSRP. Excludes select new arrivals, LITTLE PLANET®, Sneak Peek, Treasure Box, Officially Licensed Fan Shop, Licensed Character Shop, SKIP HOP®, Doorbusters and Clearance. Discount reflected in cart online.ĥ0-60% OFF ENTIRE SITE & STORE: Savings based on MSRP. Additional item of equal or lesser value. Excludes clearance, Sneak Peek and LITTLE PLANET®.īUY 1 GET 1 FREE SHOES: First item at MSRP. Excludes clearance, Sneak Peek and LITTLE PLANET®.ĥ5% OFF FASHION DENIM: Savings based on MSRP. Excludes clearance, Sneak Peek and LITTLE PLANET®.Ħ0% OFF FLEECE HOODIES & PANTS: Savings based on MSRP. Other exclusions may apply.ĥ5% OFF BABY B'GOSH: Savings based on MSRP. Excludes clearance, Sneak Peek and LITTLE PLANET®.ĥ0% OFF ENTIRE SITE & STORE: Savings based on MSRP. Excludes clearance, Sneak Peek and LITTLE PLANET®.ĥ5% OFF WORLD'S BEST OVERALLS: Savings based on MSRP. Carter's reserves the right to change or cancel this promotion at any time.Ħ5% OFF CYBER EXCLUSIVE CHRISTMAS JAMMIES: Savings based on MSRP. Prices, promotions and selections may differ from those in our retail stores. Promotion not valid on purchase of gift cards, express shipping or for shipments to U.S. Valid on only one shipping address per order. shipping on Carter's, OshKosh B'gosh and Skip Hop online orders. Other exclusions may apply.įree standard U.S. Excludes select new arrivals, LITTLE PLANET®, Sneak Peek, Treasure Box, Licensed Fan Shop, Licensed Character Shop, SKIP HOP®, Doorbusters, limited edition overalls and Clearance. Excludes clearance, Sneak Peek and LITTLE PLANET®.īUY 1, GET 1 FREE SHOES + BOOTS: First item at MSRP. Excludes clearance, Sneak Peek and LITTLE PLANET®. UP TO 70% OFF CLEARANCE: Savings based on MSRP.Ħ0% OFF LAYERING: Savings based on MSRP. Excludes Select New Arrivals, LITTLE PLANET®, Sneak Peek, Treasure Box, Licensed Styles, SKIP HOP®, Doorbusters, and Clearance. Use of bonus card is acceptance of its terms. Card will not be replaced if lost, stolen, or corrupted. If the purchase amount is less than the total amount of the gift card tendered, you surrender the full amount of the card. Gift cards cannot be used toward credit card payments. Order total after the gift card is applied must total to at least $0.01 or more to complete an online order. Gift card will be received after product has delivered, approximately within 10-12 business days. All product names and trademarks are the property of their respective owners. We reserve the right to modify or discontinue this offer at any time without notice. The value of the gift card will not be refunded on returns or exchanges. You will receive the price paid (after discount) on all returns or exchanges. Altered, duplicated, or reproduced gift cards will not be accepted. Cannot be combined, copied, transferred, or sold. Not valid on clearance, doorbuster, Treasure Box. Dollar-off discounts applied prior to percent-off total purchase discounts. Online codes are not valid on international orders. Enter promo code SPRING at checkout online at,. Earn one $10 gift card from March 29th, 2023, through April 5th, 2023, when you spend $50+ on spring new arrivals online. ![]() ![]() ![]() Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood thinners in use. Main article: Discovery and development of direct Xa inhibitors Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Īlso in contrast to warfarin and phenprocoumon, direct factor Xa inhibitors do not require frequent monitoring of the prothrombin time (also called the INR) and dose adjustments. By contrast, warfarin and phenprocoumon are often paused up to a week before surgery, and low-molecular-weight heparins are used to "bridge" the therapy gap, typically for several weeks. This means it is often possible to pause them 12 to 48 hours before surgery and resume them shortly after the surgery. They have a rapid onset and offset of action. Pharmacology Mechanism of action Coagulation in vivo, shows final common pathway and where factor Xa actsĭirect factor Xa inhibitors block the enzyme called factor Xa, preventing the conversion of prothrombin to thrombin in the final common pathway of clot formation in veins and the heart. Compared to warfarin they have fewer interactions with other medications. The blood thinning effects can be reduced if used at the same time as rifampicin and phenytoin, and increased with fluconazole. The risk of bleeding is increased if used at the same time as other blood thinning drugs such as nonsteroidal anti-inflammatory drugs, antiplatelet drugs and heparin. Andexanet alfa, a specific antidote to reverse the anticoagulant activity of direct Xa inhibitors in the event of major bleeding, was approved by the FDA in 2018. Overdose Ī specialist may request a quantitative factor Xa assay in a situation of overdose. Other side effects may include stomach upset, dizziness, anemia or increased blood levels of liver enzymes. Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. The effects on a fetus or neonate are unknown, hence these drugs are not prescribed in pregnancy or breast feeding mothers. Contraindications ĭirect Xa inhibitors are contraindicated in people who are actively bleeding or who are at high risk of bleeding. Factors considered before deciding on whether warfarin or a DOAC or which direct factor Xa inhibitor is used, include: the presence or absence of valvular heart disease, state of kidney function, the risk of stroke and the risk of bleeding. ![]() ĭirect factor Xa inhibitors can be considered as an alternative to warfarin, particularly if a person is on several other medications that interact with warfarin, or if attending medical appointments and laboratory monitoring becomes difficult. They are commonly prescribed to treat and prevent blood clots in veins, prevent stroke and embolism in people with non-valvular atrial fibrillation (AF) who have other risk factors, and prevent blood clots after routine knee and hip replacement surgery. Medical use ĭirect factor Xa inhibitors include rivaroxaban, apixaban and edoxaban, and are types of direct oral anticoagulant, which are blood thinning drugs, one of the classes of antithrombotic drugs. Inhibit fibrin formation in the final common pathway of the coagulation cascadeĭirect factor Xa inhibitors ( xabans) are anticoagulants (blood thinning drugs), used to both treat and prevent blood clots in veins, and prevent stroke and embolism in people with atrial fibrillation (AF). Direct Xa inhibitor, novel oral anticoagulant ![]() |
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